|Our research efforts are directed towards the design of novel chiral organometallic transition metal complexes, which serve as catalysts for the asymmetric synthesis of optically active organic molecules.|
Chiral Diarylamido (SO)-N-(SO) Sulfoxide Pincer
Only recently S-stereogenic sulfoxides have emerged as a versatile and encouraging novel class of ligands. Besides the proximity of the chiral information, located at the sulfur atom, to a ligated metal and thus to the reaction center, sulfoxides may switch between S and O coordination and bind to “hard” and “soft” metals, respectively. Combination of these attractive features of sulfoxides with the rigid, C2-symmetric, T-shaped configuration of a pincer scaffold leads to a promising ligand system for asymmetric catalysis.
H. Locke, A. Herrera, F. W. Heinemann, A. Linden, S. Frieß, B. Schmid, R. Dorta; Organometallics, 2015, 34, 1925-1931
F. W. Seidel, S. Frieß, F. W. Heinemann, A. Chelouan, A. Scheurer, A. Grasruck, A. Herrera, R. Dorta, Organometallics, 2018, 37, 1160-1171