Facilities
SOLID DOSAGE FORMS
– Büchi B190 laboratory spray-dryer
– Büchi B191 laboratory spray dryer
– Büchi B290 laboratory spray dryer (closed cycle)
– Niromatic Mobile Minor spray-dryer
– Pro-Cept spray dryer
– Retsch mill; Fluid energy mill
– Blenders: Turbula, Lödige, drum, cubic, Nauta
– Cylinder extruders
– Instrumented compaction blender
– Spheronizer
– 3 instrumented single-punch tablet machines
– 2 rotary tablet machines: (Kilian, Korsch)
– Niro drum coater (1.5 kg)
– Diosna mixer/granulator (2 kg)
– 2 Aeromatic fluidized-bed granulators
– Aeromatic fluidized-bed coater
– Capsule filling machine
– Blistering machine
LIQUID & SEMI-SOLID FORMS
– Sterile facility (non GMP)
– 2 Autoclaves
– Vertis Genesis freeze dryer (0.6 sqm)
– Freeze Dryer Christ Laboratory Unit
– Ampoule filling/sealing machine
– Various liquid mixers
– Microfluidizer mill
– Polymer film casting machine
– Moltomix 20kg mixer
– Planetary mixers
– Sterile facility (non GMP)
– 2 Autoclaves
– Freeze-dryer (Christ)
– Ampule filling/sealing machine
– Ultrasonic disperser & Ultraturrax mixers
– Microfluidizer
– Film casting plate
– Programmable temperature/humdity chamber
– Moltomix ointment mixer (20kg batch size)
– 2 Planetary mixers for ointment processing
SOLID DOSAGE FORMS
– Phillips wide & small-angle X-ray diffractometer
– Dielectric scanning calorimeter DeTA
– Area meter
– 2 x Karl Fischer apparatus (one with oven)
– Gas chromatograph
– 2 x Dissolution apparatus
– Friability tester, hardness tester
– Sieve tower
– Air jet sieve (Alpine)
– Air jet mill
– Electron Spectroscopy for Chemical Analysis
– Hg Porosimetry
– Controlled temperature chambers
– Cascade Impactor (Delron Research DCI6)
LIQUID & SEMI-SOLID FORMS
– 3 Size exclusion chromatographs
– 2 HPLC
– static and dynamic light scattering online detectors
– 2 x Gel electrophoresis
– Differential scanning calorimeter DSC
– Modulating differential scanning calorimeter DSC
– Mastersizer Malvern
– Thermogravimetic analysis
– Nicolet FT-IR with ATR
– 2 x Bench centrifuges (fixed & swing-out rotors)
– Thermostated Franz diffusion cells (6)
– Floor-standing small centrifuge
– 80 C Freezer
– Coulter Counter
– Inverse, fluorescence & hot-stage microscopes
– Oscillating cone-and-plate rheometer (Physica)
– Corneometer & TEWA-Meter
– Stricker absorption simulator
– Freeze-fracture table
– Scanning electron microscope (SEM)
– Access to transmission electron microscope (TEM)
– Ring tensiometer
– Krüss bubble tensiometer
– Access to circular dichroism (CD) & nmr
– Fluorimeter (protein unfolding)
– 3 x UV Spectrometer (enzyme activity assays)